Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665543 | 0.78 | MGAM (0.42) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL3498478 | 0.77 | — | — | |
| SCHEMBL5638641 | 0.77 | — | — | |
| SCHEMBL8610882 | 0.73 | CA14 (0.52) | SMN1; SMN2CA14CA12CA9KMT2A | |
| SCHEMBL3201070 | 0.73 | CA14 (0.52) | SMN1; SMN2CA14CA12CA9KMT2A | |
| SCHEMBL6008014 | 0.72 | CA1 (0.39) | SMN1; SMN2CA14CA1CA2 | |
| SCHEMBL3486105 | 0.72 | MME (0.39) | SMN1; SMN2CA14CA1CA2KMT2A | |
| SCHEMBL2702421 | 0.72 | MME (0.39) | SMN1; SMN2CA14CA1CA2KMT2A | |
| SCHEMBL3485837 | 0.72 | CA14 (0.41) | SMN1; SMN2CA14CA12CA9 | |
| SCHEMBL9033590 | 0.72 | SMN1; SMN2 (0.37) | SMN1; SMN2CA14CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705835-A1 | Quinoxalic-2,3-diones with an oxa or thiaheterocyclic fused ring | CIBA-GEIGY AG (CH) | 1996-04-10 | — | — | EP | disclosed |