Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666546 | 1.00 | ADORA1 (0.55) | ADORA1MAPK1IGF1RAKT1MAPK14 | |
| SCHEMBL7666542 | 1.00 | ADORA1 (0.55) | ADORA1MAPK1IGF1RAKT1MAPK14 | |
| SCHEMBL9034810 | 0.89 | ADORA1 (0.52) | ADORA1MAPK1IGF1RAKT1MAPK14 | |
| SCHEMBL7666482 | 0.89 | ADORA1 (0.52) | ADORA1MAPK1IGF1RAKT1MAPK14 | |
| SCHEMBL7666486 | 0.89 | ADORA1 (0.52) | ADORA1MAPK1IGF1RAKT1MAPK14 | |
| SCHEMBL7668541 | 0.87 | ADORA1 (0.53) | ADORA1MAPK1IGF1RAKT1MAPK14 | |
| SCHEMBL7659035 | 0.87 | ADORA1 (0.52) | ADORA1MAPK1IGF1RAKT1MAPK14 | |
| SCHEMBL7659023 | 0.87 | ADORA1 (0.52) | ADORA1MAPK1IGF1RAKT1MAPK14 | |
| SCHEMBL6897759 | 0.87 | ADORA1 (0.52) | ADORA1MAPK1IGF1RAKT1MAPK14 | |
| SCHEMBL7663464 | 0.86 | ADORA1 (0.53) | ADORA1MAPK1IGF1RAKT1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737193-A1 | PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018128-A1 | PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-06 | — | — | WO | disclosed |