Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035432 | 0.87 | KMT2A (0.51) | MEN1KMT2ARAD52POLBRXFP1 | |
| SCHEMBL9035288 | 0.87 | RAD52 (0.52) | MEN1KMT2ARAD52POLBRXFP1 | |
| SCHEMBL9034395 | 0.86 | RAD52 (0.56) | MEN1KMT2ARAD52POLBRXFP1 | |
| SCHEMBL9036825 | 0.85 | MEN1 (0.49) | MEN1KMT2ARAD52POLBRXFP1 | |
| SCHEMBL9035794 | 0.85 | HTR1D (0.49) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL9034861 | 0.80 | KDM4E (0.47) | MEN1KMT2ARAD52POLBRXFP1 | |
| SCHEMBL9033650 | 0.80 | KDM4E (0.47) | MEN1KMT2ARAD52POLBRXFP1 | |
| SCHEMBL9035214 | 0.80 | MEN1 (0.47) | MEN1KMT2ARAD52POLBRXFP1 | |
| SCHEMBL9033610 | 0.78 | MEN1 (0.45) | MEN1KMT2ARAD52POLBRXFP1 | |
| SCHEMBL8876713 | 0.76 | TSHR (0.53) | POLBGAAALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |