Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041705 | 0.86 | HTR1D (0.77) | HTR1D | |
| SCHEMBL7040794 | 0.85 | HTR1D (1.00) | HTR1D | |
| SCHEMBL7041180 | 0.82 | SLC6A4 (0.59) | HTR1D | |
| SCHEMBL7041675 | 0.81 | HTR1D (0.69) | HTR1D | |
| SCHEMBL8193767 | 0.81 | HTR1D (0.65) | HTR1D | |
| SCHEMBL9170864 | 0.81 | HTR1D (0.62) | HTR1D | |
| SCHEMBL7040750 | 0.80 | GRIN2B (0.53) | HTR1D | |
| SCHEMBL8192046 | 0.79 | HTR1D (0.68) | HTR1D | |
| SCHEMBL7038388 | 0.79 | HTR1D (0.88) | HTR1D | |
| SCHEMBL7036364 | 0.79 | HTR1D (0.68) | HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546583-B1 | Piperazinyl-and piperidinyl-cyclohexanols | BRISTOL MYERS SQUIBB CO (US) | 1996-05-22 | — | — | EP | claimed |
| US-5387593-A | Anxiolytic agents | BRISTON-MYERS SQUIBB (US) | 1995-02-07 | — | — | US | claimed |
| EP-0546583-A1 | Piperazinyl-and piperidinyl-cyclohexanols | Bristol-Myers Squibb Company (US) | 1993-06-16 | — | — | EP | claimed |
| JP-6080634-A | — | — | None | — | — | JP | disclosed |
| EP-0546583-B1 | Piperazinyl-and piperidinyl-cyclohexanols | BRISTOL MYERS SQUIBB CO (US) | 1996-05-22 | — | — | EP | disclosed |
| US-5478828-A | Anxiolytic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-12-26 | — | — | US | disclosed |
| US-5387593-A | Anxiolytic agents | BRISTON-MYERS SQUIBB (US) | 1995-02-07 | — | — | US | disclosed |
| JP-H0680634-A | PIPERAZINYL-AND PIPERIDINYL-CYCLOHEXANOL COMPOUNDS | BRISTOL MYERS SQUIBB CO | 1994-03-22 | — | — | JP | disclosed |
| EP-0546583-A1 | Piperazinyl-and piperidinyl-cyclohexanols | Bristol-Myers Squibb Company (US) | 1993-06-16 | — | — | EP | disclosed |