Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671446 | 0.92 | CYP4F2 (0.47) | CYP4F2CYP4A11TSHRPOLBALDH1A1 | |
| SCHEMBL432804 | 0.90 | CYP4F2 (0.50) | CYP4F2CYP4A11TSHRPOLBALDH1A1 | |
| SCHEMBL16294203 | 0.87 | POLB (0.48) | POLBALDH1A1HPGDHDAC1MAPT | |
| SCHEMBL6036442 | 0.84 | POLB (0.56) | CYP4F2CYP4A11TSHRPOLBALDH1A1 | |
| SCHEMBL490458 | 0.84 | HSD17B10 (0.55) | CYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL13647141 | 0.83 | POLB (0.50) | POLBHPGDNPC1RAB9AHDAC1 | |
| SCHEMBL30839903 | 0.83 | POLB (0.50) | POLBHPGDNPC1RAB9AHDAC1 | |
| SCHEMBL4508144 | 0.83 | CYP4F2 (0.49) | CYP4F2CYP4A11TSHRPOLBALDH1A1 | |
| SCHEMBL1886489 | 0.83 | CYP4F2 (0.49) | CYP4F2CYP4A11TSHRPOLBALDH1A1 | |
| SCHEMBL3903179 | 0.83 | CYP4F2 (0.52) | CYP4F2CYP4A11TSHRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484481-B | Synthesis method of dihydro-1H-indene spiro compound | 遵义医学院 | 2020-06-12 | — | — | CN | disclosed |
| EP-0422134-B1 | 5-HT SELECTIVE AGENTS | ABBOTT LAB (US) | 1996-06-12 | — | — | EP | disclosed |