Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | NAAA | Q02083 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037484 | 1.00 | HPGD (0.55) | HPGDNAAAMAPTCASP2FAAH | |
| SCHEMBL8966708 | 1.00 | HPGD (0.55) | HPGDNAAAMAPTCASP2FAAH | |
| SCHEMBL8966869 | 1.00 | HPGD (0.55) | HPGDNAAAMAPTCASP2FAAH | |
| SCHEMBL8966319 | 1.00 | HPGD (0.55) | HPGDNAAAMAPTCASP2FAAH | |
| SCHEMBL9037432 | 1.00 | HPGD (0.55) | HPGDNAAAMAPTCASP2FAAH | |
| SCHEMBL8966714 | 0.96 | HPGD (0.56) | HPGDNAAAMAPTCASP2FAAH | |
| SCHEMBL8967192 | 0.96 | HPGD (0.56) | HPGDNAAAMAPTCASP2FAAH | |
| SCHEMBL8967177 | 0.96 | HPGD (0.56) | HPGDNAAAMAPTCASP2FAAH | |
| SCHEMBL8966750 | 0.96 | HPGD (0.56) | HPGDNAAAMAPTCASP2FAAH | |
| SCHEMBL8966739 | 0.96 | HPGD (0.56) | HPGDNAAAMAPTCASP2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522606-B1 | Pyridine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-04-03 | — | — | EP | disclosed |