Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035632 | 1.00 | FGFR2 (0.34) | FGFR2NSD2GRM1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8707219 | 0.99 | FGFR2 (0.34) | FGFR2NSD2GRM1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8710432 | 0.99 | FGFR2 (0.34) | FGFR2NSD2GRM1DRD2DRD3 | |
| SCHEMBL8705285 | 0.89 | NSD2 (0.35) | FGFR2NSD2GRM1DRD2DRD3 | |
| SCHEMBL8705288 | 0.89 | NSD2 (0.35) | FGFR2NSD2GRM1DRD2DRD3 | |
| SCHEMBL8706052 | 0.88 | FGFR2 (0.34) | FGFR2NSD2GRM1DRD2DRD3 | |
| SCHEMBL9034335 | 0.87 | NSD2 (0.36) | FGFR2NSD2GRM1DRD2DRD3 | |
| SCHEMBL8710322 | 0.87 | NSD2 (0.36) | FGFR2NSD2GRM1DRD2DRD3 | |
| SCHEMBL8710207 | 0.87 | NSD2 (0.36) | FGFR2NSD2GRM1DRD2DRD3 | |
| SCHEMBL8417988 | 0.86 | FGFR2 (0.44) | FGFR2NSD2GRM1MAOACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719256-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007891-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |