Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 12/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 12/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | PDE5A | O76074 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTAFR | P25105 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PDE1A | P54750 | 1/20 | 0.55 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035597 | 0.94 | PDE3B (0.58) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL9036046 | 0.94 | PDE3B (0.58) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL9035142 | 0.91 | PDE3B (0.56) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL9035168 | 0.91 | PDE3B (0.56) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL9038129 | 0.87 | PDE3B (0.53) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL9035550 | 0.87 | PDE3B (0.53) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL9043940 | 0.86 | PDE3B (0.57) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| Oxalic Acid SCHEMBL9035547 | 0.86 | PDE3B (0.52) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL9036148 | 0.86 | PDE3B (0.62) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL9035980 | 0.85 | PDE3B (0.60) | PDE3BPDE3AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |