Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040794 | 0.85 | HTR1D (1.00) | HTR1D | |
| SCHEMBL8192035 | 0.79 | HTR1D (0.88) | HTR1D | |
| SCHEMBL7038388 | 0.79 | HTR1D (0.88) | HTR1D | |
| SCHEMBL8192036 | 0.79 | HTR1D (0.88) | HTR1D | |
| SCHEMBL9035305 | 0.79 | HTR1D (1.00) | HTR1D | |
| SCHEMBL7038222 | 0.78 | HTR1D (0.63) | HTR1D | |
| SCHEMBL7036322 | 0.75 | HTR1D (0.80) | HTR1D | |
| SCHEMBL7040198 | 0.75 | HTR1D (0.80) | HTR1D | |
| SCHEMBL9036226 | 0.75 | HTR1D (0.76) | HTR1D | |
| Hydrochloric Acid SCHEMBL11870563 | 0.74 | HTR1D (0.55) | HTR1DTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546583-B1 | Piperazinyl-and piperidinyl-cyclohexanols | BRISTOL MYERS SQUIBB CO (US) | 1996-05-22 | — | — | EP | claimed |
| EP-0546583-A1 | Piperazinyl-and piperidinyl-cyclohexanols | Bristol-Myers Squibb Company (US) | 1993-06-16 | — | — | EP | claimed |
| EP-0546583-B1 | Piperazinyl-and piperidinyl-cyclohexanols | BRISTOL MYERS SQUIBB CO (US) | 1996-05-22 | — | — | EP | disclosed |
| US-5478828-A | Anxiolytic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-12-26 | — | — | US | disclosed |
| US-5387593-A | Anxiolytic agents | BRISTON-MYERS SQUIBB (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0546583-A1 | Piperazinyl-and piperidinyl-cyclohexanols | Bristol-Myers Squibb Company (US) | 1993-06-16 | — | — | EP | disclosed |