Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035842 | 1.00 | KMT2A (0.40) | KMT2ACHRNB2CHRNA4KDM4ETSHR | |
| SCHEMBL8377074 | 1.00 | KMT2A (0.40) | KMT2ACHRNB2CHRNA4KDM4ETSHR | |
| SCHEMBL4216297 | 0.88 | KMT2A (0.44) | KMT2ACHRNB2CHRNA4KDM4ETSHR | |
| SCHEMBL9777782 | 0.78 | BLM (0.42) | KMT2AKDM4ETSHRHTTHSD17B10 | |
| SCHEMBL6570119 | 0.78 | BLM (0.42) | KMT2AKDM4ETSHRHTTHSD17B10 | |
| SCHEMBL16635019 | 0.77 | — | — | |
| SCHEMBL7851396 | 0.77 | KMT2A (0.37) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL27563591 | 0.77 | KMT2A (0.37) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL11358106 | 0.76 | KMT2A (0.42) | KMT2ACHRNB2CHRNA4KDM4ETSHR | |
| SCHEMBL3587732 | 0.74 | TSHR (0.40) | KMT2ACHRNB2CHRNA4KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |