Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721716 | 0.86 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL9036377 | 0.80 | NPC1 (0.40) | TLR7 | |
| SCHEMBL7837869 | 0.79 | TLR7 (0.72) | TLR7TLR8NUDT1 | |
| SCHEMBL8811709 | 0.75 | TLR7 (0.79) | TLR7TLR8 | |
| SCHEMBL8722625 | 0.73 | TLR7 (0.62) | TLR7TLR8NUDT1 | |
| SCHEMBL18292495 | 0.72 | TLR7 (0.71) | TLR7TLR8NUDT1 | |
| SCHEMBL29605454 | 0.72 | TLR7 (0.65) | TLR7TLR8NUDT1 | |
| SCHEMBL22898837 | 0.72 | TLR7 (0.65) | TLR7TLR8NUDT1 | |
| SCHEMBL6722230 | 0.72 | TLR7 (0.77) | TLR7TLR8 | |
| SCHEMBL19345034 | 0.71 | TLR7 (0.76) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385630-B1 | 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals | RIKER LABORATORIES INC (US) | 1996-11-27 | — | — | EP | disclosed |
| EP-0389302-B1 | Olefinic 1H-imidazo [4,5-c]quinolin-4-amines | RIKER LABORATORIES INC (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5037986-A | Olefinic 1H-imidazo[4,5-c]quinolin-4-amines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0389302-A1 | Olefinic 1H-imidazo [4,5-c]quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| EP-0385630-A2 | 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals | RIKER LABORATORIES, INC. (US) | 1990-09-05 | — | — | EP | disclosed |