SCHEMBL9036302

SCHEMBL9036302

[CH2]C(C)CN1CCSCC1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39
POLB P06746 1/20 0.35
DPP4 P27487 4/20 0.31
DPP7 Q9UHL4 3/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
DPP8 Q6V1X1 2/20 0.30
DPP9 Q86TI2 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11501775 0.82 PIK3CD (0.39) POLBKDM4EALDH1A1L3MBTL1MEN1
SCHEMBL201003 0.80 PIK3CD (0.45) GAAPOLBKDM4EALDH1A1L3MBTL1
SCHEMBL4967511 0.77
SCHEMBL10442183 0.76 GAA (0.39) GAAPOLBDPP4DPP7KDM4E
SCHEMBL357640 0.76 DPP4 (0.39) GAAPOLBDPP4DPP7KDM4E
SCHEMBL9124652 0.76 GAA (0.39) GAAPOLBKDM4EALDH1A1L3MBTL1
SCHEMBL18685417 0.76 GAA (0.39) GAAPOLBKDM4EALDH1A1L3MBTL1
SCHEMBL10290926 0.76 GAA (0.39) GAAPOLBKDM4EALDH1A1L3MBTL1
SCHEMBL14160640 0.76 GAA (0.39) GAAPOLBMEN1KMT2A
SCHEMBL2730636 0.76 DPP4 (0.39) GAAPOLBDPP4DPP7KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450066-B1 CARBOSTYRIL DERIVATIVES OTSUKA PHARMA CO LTD (JP) 1996-09-11 EP disclosed
US-5401740-A FOR INHIBITING PLATELET AGGREGATION OTSUKA PHARMACEUTICAL CO. (JP) 1995-03-28 US disclosed
US-5227381-A Anticoagulant OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-13 US disclosed
EP-0450066-A1 CARBOSTYRIL DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-10-09 EP disclosed