Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADH1B | P00325 | 2/20 | 0.41 |
| ▸ | ADH1C | P00326 | 2/20 | 0.41 |
| ▸ | ADH1A | P07327 | 2/20 | 0.41 |
| ▸ | ADH7 | P40394 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15383250 | 1.00 | KDM1A (0.56) | KDM1ATSHRALDH1A1ADH1BADH1C | |
| SCHEMBL24414938 | 0.94 | KDM1A (0.59) | KDM1ATSHRALDH1A1ADH1BADH1C | |
| SCHEMBL24131906 | 0.93 | KDM1A (0.58) | KDM1ATSHRALDH1A1ADH1BADH1C | |
| SCHEMBL11403842 | 0.91 | KDM1A (0.61) | KDM1ATSHRALDH1A1ADH1BADH1C | |
| SCHEMBL9213042 | 0.91 | KDM1A (0.61) | KDM1ATSHRALDH1A1ADH1BADH1C | |
| SCHEMBL8927039 | 0.90 | KDM1A (0.67) | KDM1ATSHRALDH1A1ADH1BADH1C | |
| SCHEMBL8637645 | 0.85 | KDM1A (0.68) | KDM1ATSHRALDH1A1ADH1BADH1C | |
| SCHEMBL22473042 | 0.85 | KDM1A (0.48) | KDM1AALDH1A1ADH1BADH1AADH7 | |
| SCHEMBL8637649 | 0.85 | KDM1A (0.68) | KDM1ATSHRALDH1A1ADH1BADH1C | |
| SCHEMBL12978077 | 0.85 | KDM1A (0.50) | KDM1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |