Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19225801 | 1.00 | NR1H4 (0.32) | NR1H4HPGDSSSTR3MAPK13MAPK12 | |
| SCHEMBL18978473 | 1.00 | NR1H4 (0.32) | NR1H4HPGDSSSTR3MAPK13MAPK12 | |
| SCHEMBL10215164 | 1.00 | NR1H4 (0.32) | NR1H4HPGDSSSTR3MAPK13MAPK12 | |
| SCHEMBL18057078 | 1.00 | NR1H4 (0.32) | NR1H4HPGDSSSTR3MAPK13MAPK12 | |
| SCHEMBL903494 | 1.00 | NR1H4 (0.32) | NR1H4HPGDSSSTR3MAPK13MAPK12 | |
| SCHEMBL19225806 | 1.00 | NR1H4 (0.32) | NR1H4HPGDSSSTR3MAPK13MAPK12 | |
| SCHEMBL18057083 | 1.00 | NR1H4 (0.32) | NR1H4HPGDSSSTR3MAPK13MAPK12 | |
| SCHEMBL10219365 | 0.94 | PRCP (0.33) | NR1H4HPGDSPRCP | |
| SCHEMBL10219362 | 0.94 | CDC7 (0.34) | SSTR3PRCP | |
| SCHEMBL18978436 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041014-A1 | TETRACYCLIC INDOLE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |