Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 10/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036091 | 0.99 | POLB (0.41) | S1PR5S1PR1S1PR3POLBGSK3B | |
| SCHEMBL9036080 | 0.97 | POLB (0.43) | S1PR5S1PR1S1PR3POLBMMP1 | |
| SCHEMBL9493240 | 0.94 | POLB (0.43) | S1PR5S1PR1S1PR3POLBMMP1 | |
| SCHEMBL9036911 | 0.90 | POLB (0.44) | POLB | |
| SCHEMBL9036325 | 0.87 | POLB (0.43) | S1PR5S1PR1S1PR3POLBGSK3B | |
| SCHEMBL9493789 | 0.86 | POLB (0.46) | POLBGSK3B | |
| SCHEMBL9035970 | 0.86 | POLB (0.42) | S1PR5S1PR1POLB | |
| SCHEMBL9036684 | 0.85 | POLB (0.45) | POLBGSK3B | |
| SCHEMBL9036104 | 0.84 | GSK3B (0.52) | S1PR5S1PR1S1PR3POLBGSK3B | |
| SCHEMBL9491735 | 0.84 | POLB (0.44) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492667-B1 | 1,4-Benzothiazine-2-acetic acid derivatives, processes for production thereof and their use | GREEN CROSS CORP (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5252571-A | 1,4-benzothiazine-2-acetic acid derivatives | SAPPORO BREWERIES LIMITED (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0492667-A1 | 1,4-Benzothiazine-2-acetic acid derivatives, processes for production thereof and their use | THE GREEN CROSS CORPORATION (JP) | 1992-07-01 | — | — | EP | disclosed |