Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 3/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.32 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | HRAS | P01112 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039671 | 1.00 | BDKRB1 (0.38) | BDKRB1GRM1TOP1HRASESR1 | |
| Hydrochloric Acid SCHEMBL7808947 | 0.99 | BDKRB1 (0.37) | BDKRB1GRM1TOP1HRASESR1 | |
| Hydrochloric Acid SCHEMBL9038724 | 0.99 | BDKRB1 (0.37) | BDKRB1GRM1TOP1HRASESR1 | |
| SCHEMBL9040554 | 0.88 | HRAS (0.36) | BDKRB1TOP1HRASESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7840873 | 0.85 | BDKRB1 (0.35) | BDKRB1GRM1 | |
| SCHEMBL9038538 | 0.83 | BDKRB1 (0.34) | BDKRB1 | |
| SCHEMBL9038066 | 0.83 | BDKRB1 (0.33) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL7834143 | 0.83 | BDKRB1 (0.33) | BDKRB1 | |
| SCHEMBL9038576 | 0.83 | BDKRB1 (0.33) | BDKRB1 | |
| SCHEMBL9037076 | 0.83 | BDKRB1 (0.33) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722446-A1 | DISTAMYCIN A ANALOGUES AS ANTITUMOUR OR ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996005196-A1 | DISTAMYCIN A ANALOGUES AS ANTITUMOUR OR ANTIVIRAL AGENTS | PHARMACIA S.P.A. (IT) | 1996-02-22 | — | — | WO | disclosed |