Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037297 | 1.00 | ELANE (0.52) | ELANEMEN1KMT2AALDH1A1ADORA3 | |
| SCHEMBL9037300 | 1.00 | ELANE (0.52) | ELANEMEN1KMT2AALDH1A1ADORA3 | |
| SCHEMBL5743179 | 0.90 | ELANE (0.49) | ELANEMEN1KMT2AALDH1A1ADORA3 | |
| SCHEMBL5743187 | 0.90 | ELANE (0.49) | ELANEMEN1KMT2AALDH1A1ADORA3 | |
| SCHEMBL5743190 | 0.90 | ELANE (0.49) | ELANEMEN1KMT2AALDH1A1ADORA3 | |
| SCHEMBL9898311 | 0.88 | ELANE (0.47) | ELANEMEN1KMT2AKDM4EGAA | |
| SCHEMBL6860153 | 0.87 | ELANE (0.47) | ELANEALDH1A1ADORA3LMNAKDM4E | |
| SCHEMBL6860155 | 0.87 | ELANE (0.47) | ELANEALDH1A1ADORA3LMNAKDM4E | |
| SCHEMBL6860152 | 0.87 | ELANE (0.47) | ELANEALDH1A1ADORA3LMNAKDM4E | |
| SCHEMBL6333635 | 0.86 | ELANE (0.46) | ELANERECQLKDM4EGAAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534707-B1 | Alkoxy substituted taxanes as antitumour agents | UNIV FLORIDA STATE (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5243045-A | Antitumor agents | FLORIDA STATE UNIVERSITY (US) | 1993-09-07 | — | — | US | disclosed |
| US-5229526-A | METAL ALKOXIDES | FLORIDA STATE UNIVERSITY (US) | 1993-07-20 | — | — | US | disclosed |