Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.61 |
| ▸ | CNR1 | P21554 | 8/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037258 | 0.84 | CNR2 (0.72) | CNR2CNR1 | |
| SCHEMBL15112248 | 0.76 | CNR2 (0.70) | CNR2CNR1 | |
| Water SCHEMBL9037716 | 0.76 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL3820957 | 0.74 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL9641383 | 0.72 | CNR2 (0.63) | CNR2CNR1 | |
| SCHEMBL9691579 | 0.72 | CNR1 (0.73) | CNR2CNR1 | |
| SCHEMBL7217660 | 0.72 | CNR2 (0.81) | CNR2CNR1 | |
| SCHEMBL12782517 | 0.72 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL5463245 | 0.71 | CNR2 (0.52) | CNR2CNR1 | |
| SCHEMBL9036015 | 0.71 | CNR1 (0.74) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445781-B1 | 3-Arylcarbonyl-1-aminoalkyl-1H-indole containing antiglaucoma compositions | STERLING WINTHROP INC (US) | 1996-01-31 | — | — | EP | disclosed |
| EP-0445781-A1 | 3-Arylcarbonyl-1-aminoalkyl-1H-indole containing antiglaucoma compositions | STERLING WINTHROP INC. (US) | 1991-09-11 | — | — | EP | disclosed |
| US-5013837-A | Treatment of glaucoma | STERLING DRUG INC. (US) | 1991-05-07 | — | — | US | disclosed |
| US-4973587-A | 3-arylcarbonyl-1-aminoalkyl-1H-indole-containing antiglaucoma method | STERLING DRUG INC. (US) | 1990-11-27 | — | — | US | disclosed |