Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 15/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL9039827 | 1.00 | DRD1 (0.45) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL8829246 | 0.89 | DRD1 (0.50) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL7440991 | 0.89 | DRD1 (0.50) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| Formic Acid SCHEMBL9670061 | 0.88 | DRD1 (0.46) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| Formic Acid SCHEMBL9040351 | 0.88 | DRD1 (0.46) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL7443896 | 0.78 | DRD1 (0.35) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL9040854 | 0.76 | KDM1A (0.35) | — | |
| SCHEMBL9042337 | 0.76 | KDM1A (0.35) | — | |
| SCHEMBL10380390 | 0.73 | DRD1 (0.34) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL7439138 | 0.69 | KDM1A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474767-B1 | DOPAMINE AGONISTS | ABBOTT LAB (US) | 1996-02-21 | — | — | EP | disclosed |
| WO-1990015056-A1 | DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1990-12-13 | — | — | WO | disclosed |