Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642249 | 0.90 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL8697401 | 0.88 | EDNRB (0.65) | EDNRBEDNRA | |
| SCHEMBL6638555 | 0.86 | EDNRB (0.92) | EDNRBEDNRA | |
| SCHEMBL9039419 | 0.86 | EDNRB (0.72) | EDNRBEDNRA | |
| SCHEMBL9038310 | 0.84 | EDNRB (0.83) | EDNRBEDNRA | |
| SCHEMBL6639249 | 0.84 | EDNRB (0.87) | EDNRBEDNRA | |
| SCHEMBL6640358 | 0.83 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL8686074 | 0.81 | EDNRA (0.81) | EDNRBEDNRA | |
| SCHEMBL7949154 | 0.80 | EDNRA (0.70) | EDNRBEDNRA | |
| SCHEMBL6639342 | 0.80 | EDNRB (1.00) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725067-A1 | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-07 | — | — | EP | claimed |
| EP-0725067-A1 | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-07 | — | — | EP | disclosed |