Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 6/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LGMN | Q99538 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693127 | 0.83 | PDE3B (0.49) | PDE3BPDE3AKMT2APARP1 | |
| SCHEMBL15917986 | 0.78 | PDE3B (0.80) | PDE3BPDE3ATHRB | |
| SCHEMBL27093179 | 0.70 | PDE3B (0.49) | PDE3BPDE3APOLBPABPC1LGMN | |
| SCHEMBL15917628 | 0.70 | PDE3B (1.00) | PDE3BPDE3AGAAKMT2ALGMN | |
| SCHEMBL15918409 | 0.70 | PDE3B (1.00) | PDE3BPDE3APOLBPABPC1GAA | |
| SCHEMBL15917778 | 0.68 | PDE3B (0.80) | PDE3BPDE3AGAAHTTKDM4E | |
| SCHEMBL15917702 | 0.67 | PDE3B (0.78) | PDE3BPDE3APOLBHTT | |
| SCHEMBL15917457 | 0.67 | PDE3B (1.00) | PDE3BPDE3APOLBKMT2ARXFP1 | |
| SCHEMBL15930074 | 0.67 | PDE3B (0.78) | PDE3BPDE3AGAATHRB | |
| SCHEMBL15917729 | 0.67 | PDE3B (1.00) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736569-A1 | Derivatives of pyrrolodiazine as stabilisers for polymers containing chlorine | CIBA-GEIGY AG (CH) | 1996-10-09 | — | — | EP | disclosed |