⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043291 | 0.86 | — | — | |
| SCHEMBL9041679 | 0.83 | — | — | |
| SCHEMBL9044972 | 0.82 | — | — | |
| SCHEMBL9043504 | 0.81 | CYP2D6 (0.30) | — | |
| SCHEMBL8849619 | 0.75 | CYP2D6 (0.38) | — | |
| SCHEMBL9482013 | 0.71 | CYP1A2 (0.33) | — | |
| SCHEMBL7007416 | 0.71 | — | — | |
| SCHEMBL9347229 | 0.70 | CYP2D6 (0.54) | — | |
| SCHEMBL9472706 | 0.69 | CYP2D6 (0.33) | — | |
| SCHEMBL9347249 | 0.69 | CYP2D6 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480204-B1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5215994-A | Treating or preventing hypertension or heart failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5210092-A | Hypotensive agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0480204-A1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |