Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28745869 | 0.90 | S1PR3 (0.63) | CYSLTR2CYSLTR1CYP19A1S1PR3THRA | |
| SCHEMBL27545224 | 0.88 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1CYP19A1S1PR3RAB9A | |
| SCHEMBL27518496 | 0.88 | MAPT (0.59) | CYSLTR2CYSLTR1CYP19A1S1PR3RAB9A | |
| SCHEMBL7970263 | 0.88 | S1PR3 (0.61) | CYSLTR2CYSLTR1CYP19A1S1PR3PTPN11 | |
| SCHEMBL27571908 | 0.87 | CYP19A1 (0.56) | CYSLTR2CYSLTR1CYP19A1S1PR3RAB9A | |
| SCHEMBL16430716 | 0.87 | MAPT (0.57) | CYSLTR2CYSLTR1CYP19A1S1PR3RAB9A | |
| SCHEMBL7970564 | 0.86 | CYP19A1 (0.54) | CYSLTR2CYSLTR1CYP19A1S1PR3RAB9A | |
| SCHEMBL5016734 | 0.85 | CYP3A4 (0.54) | RAB9ALMNAMAPTKMT2AMEN1 | |
| SCHEMBL9127581 | 0.83 | CYP19A1 (0.66) | CYSLTR2CYSLTR1CYP19A1RAB9ATHRA | |
| SCHEMBL9165752 | 0.83 | CYP19A1 (0.66) | CYSLTR2CYSLTR1CYP19A1RAB9ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367498-B1 | Photographic material and process comprising a pyrazoloazole dyeforming coupler | EASTMAN KODAK CO (US) | 1996-06-19 | — | — | EP | disclosed |
| EP-0367498-A2 | Photographic material and process comprising a pyrazoloazole dyeforming coupler | EASTMAN KODAK COMPANY (US) | 1990-05-09 | — | — | EP | disclosed |