Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038288 | 1.00 | TSHR (0.47) | TSHRNPSR1TDP1HTTPOLB | |
| SCHEMBL9038592 | 0.99 | TSHR (0.48) | TSHRNPSR1TDP1HTTPOLB | |
| SCHEMBL9038944 | 0.96 | TSHR (0.48) | TSHRNPSR1TDP1HTTPOLB | |
| SCHEMBL8061740 | 0.93 | TSHR (0.50) | TSHRNPSR1HTTMAPTLMNA | |
| SCHEMBL9039596 | 0.91 | MAPT (0.53) | TSHRHTTMAPTLMNAALDH1A1 | |
| SCHEMBL9041873 | 0.91 | MAPT (0.53) | TSHRHTTMAPTLMNAALDH1A1 | |
| SCHEMBL9041002 | 0.89 | MAPT (0.54) | TSHRHTTMAPTLMNAALDH1A1 | |
| SCHEMBL9039604 | 0.89 | TSHR (0.47) | TSHRNPSR1HTTMAPTLMNA | |
| SCHEMBL9040330 | 0.89 | TSHR (0.47) | TSHRNPSR1HTTMAPTLMNA | |
| SCHEMBL13346921 | 0.88 | TSHR (0.41) | TSHRNPSR1TDP1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385456-B1 | High surface hardness transparent resin and polymerizable monomer | MITSUI TOATSU CHEMICALS (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5440358-A | Scratch, heat, chemical resistant crosslinked copolymer | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5260439-A | With acrylic ester | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5084538-A | HIGH SURFACE HARDNESS TRANSPARENT RESIN PREPARED FROM A COMPOUND HAVING AT LEAST ONE ISOPROPENYL PHENYL GROUP | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0385456-A2 | High surface hardness transparent resin and polymerizable monomer | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-09-05 | — | — | EP | disclosed |