SCHEMBL904080

SCHEMBL904080

CCN(CC)CCCCNc1cc[n+](CC)c2cc(Cl)ccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CCR4 P51679 1/20 0.40
FERMT2 Q96AC1 1/20 0.40
CCR1 P32246 1/20 0.40
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PRNP P04156 1/20 0.38
APP P05067 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
NQO2 P16083 1/20 0.38
ADRA2B P18089 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL901715 0.99 CDK1 (0.47) CDK1KDM4ELMNAHTTHSD17B10
SCHEMBL1147601 0.74 KDM4E (0.84) CDK1KDM4ELMNAHTTHSD17B10
SCHEMBL1147600 0.73 KDM4E (0.82) CDK1KDM4ELMNAHTTHSD17B10
SCHEMBL1147663 0.73 KDM4E (0.82) CDK1KDM4ELMNAHTTHSD17B10
SCHEMBL1147009 0.72 CDK1 (0.81) CDK1KDM4ELMNAHTTHSD17B10
SCHEMBL1147618 0.71 CDK1 (0.80) CDK1KDM4ELMNAHTTHSD17B10
SCHEMBL1147537 0.71 CDK1 (0.80) CDK1KDM4ELMNAHTTHSD17B10
Water SCHEMBL14739890 0.71 CCR1 (0.52) FERMT2CCR1NR4A2
SCHEMBL8148976 0.70 CDK1 (0.52) CDK1KDM4ELMNAHTTHSD17B10
SCHEMBL1147366 0.70 CDK1 (0.87) CDK1KDM4ELMNAHTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012041493-A1 AMINOQUINOLINIUM SALTS, METHODS OF THEIR PRODUCTION AND THEIR USE AS ACTIVE AGENTS FOR BIOTECHNOLOGICAL AND MEDICAL APPLICATIONS AGAINST BINARY TOXINS JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) 2012-04-05 WO disclosed