Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.67 |
| ▸ | HTR2C | P28335 | 1/20 | 0.67 |
| ▸ | PPARG | P37231 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.65 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.65 |
| ▸ | ALB | P02768 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 3/20 | 0.64 |
| ▸ | ESR1 | P03372 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 3/20 | 0.58 |
| ▸ | APAF1 | O14727 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.58 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040843 | 1.00 | NR1I2 (0.67) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL9871538 | 0.94 | NR1I2 (0.72) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL9871550 | 0.94 | NR1I2 (0.72) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL9692862 | 0.94 | NR1I2 (0.68) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL9692674 | 0.89 | NR1I2 (0.70) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| Water SCHEMBL9343390 | 0.89 | NR1I2 (0.80) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL9692663 | 0.89 | NR1I2 (0.70) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL11060892 | 0.89 | NR1I2 (0.70) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL11060900 | 0.89 | NR1I2 (0.70) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| Water SCHEMBL9343404 | 0.89 | NR1I2 (0.80) | NR1I2HTR2CPPARGMAPTSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412763-B1 | Cephalosporins, processes for their preparation, pharmaceutical compositions containing them and intermediates therefor | ZENECA LTD (GB) | 1996-07-10 | — | — | EP | disclosed |
| US-5219848-A | Bactericides | ICI PHARMA (FR) | 1993-06-15 | — | — | US | disclosed |
| EP-0412763-A2 | Cephalosporins, processes for their preparation, pharmaceutical compositions containing them and intermediates therefor | ZENECA LIMITED (GB) | 1991-02-13 | — | — | EP | disclosed |