SCHEMBL9040952

SCHEMBL9040952

CCc1ccc2ccc3ccccc3c2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.65
CYP2A6 P11509 2/20 0.65
ALDH1A1 P00352 4/20 0.56
HSD17B10 Q99714 3/20 0.56
HIF1A Q16665 2/20 0.56
CYP1B1 Q16678 1/20 0.56
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP2D6 P10635 3/20 0.50
CYP2C19 P33261 2/20 0.50
KIF11 P52732 1/20 0.48
HPRT1 P00492 1/20 0.48
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
CNR2 P34972 3/20 0.45
GAA P10253 1/20 0.43
CASP3 P42574 1/20 0.43
GFER P55789 1/20 0.43
SENP8 Q96LD8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598696 0.89 CYP1A2 (0.69) CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A
SCHEMBL19583369 0.89 CYP2A6 (0.58) CYP1A2CYP2A6ALDH1A1TSHRKIF11
SCHEMBL7773085 0.88 CYP1A2 (0.67) CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A
SCHEMBL1898791 0.88 CYP1A2 (0.67) CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A
SCHEMBL9765513 0.84 CYP1A2 (0.57) CYP1A2CYP2A6ALDH1A1HIF1ACYP2D6
SCHEMBL19583381 0.83 CYP1A2 (0.56) CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A
Phenanthrene SCHEMBL28839877 0.82 TP53 (0.67) CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A
SCHEMBL19583366 0.80 CYP1A2 (0.61) CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A
SCHEMBL28499910 0.80 CYP1A2 (0.53) CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A
SCHEMBL73386 0.79 CYP2A6 (1.00) CYP1A2CYP2A6ALDH1A1TDP1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112485343-A Underground water hydrocarbon pollutant source tracing method and system 长江大学 2021-03-12 CN disclosed
CN-109071731-A Polymerizable composition, polymerizable composition containing reactivity silesquioxane compound containing phenanthrene ring 日产化学株式会社 2018-12-21 CN disclosed
US-20170329220-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE ELEMENT, CURED PRODUCT, SEMICONDUCTOR DEVICE, METHOD FOR FORMING RESIST PATTERN, AND METHOD FOR PRODUCING CIRCUIT SUBSTRATE HITACHI CHEMICAL COMPANY, LTD. (JP) 2017-11-16 US disclosed
EP-0705250-A1 BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-04-10 EP disclosed