Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.56 |
| ▸ | CHRNG | P07510 | 1/20 | 0.56 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | CHRND | Q07001 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | C1S | P09871 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22557048 | 0.98 | PARP1 (0.56) | PARP1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL28007604 | 0.85 | PARP1 (0.62) | PARP1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL29922182 | 0.85 | CHRNA1 (0.59) | PARP1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL3125040 | 0.85 | CHRNA1 (0.59) | PARP1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL2599175 | 0.83 | CHRNA1 (0.58) | PARP1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL30310283 | 0.83 | CHRNA1 (0.58) | PARP1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL15007152 | 0.83 | CHRNA1 (0.58) | PARP1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL633367 | 0.83 | CHRNA1 (0.58) | PARP1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL8398736 | 0.81 | PARP1 (0.58) | PARP1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL4665718 | 0.81 | CHRNA1 (0.56) | PARP1CHRNA1CHRNGCHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031941-C | Process for preparing fluoroethylcamptothecin derivatives | KYORIN SEIYAKU KK (JP) | 1996-06-05 | — | — | CN | disclosed |
| EP-0471358-B1 | Fluoroethylcamptothecin derivatives | KYORIN SEIYAKU KK (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0325247-B1 | CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1993-05-19 | — | — | EP | disclosed |
| CN-1060095-A | Fluoroethylcamptothederivatives derivatives | KYORIN SEIYAKU KK (JP) | 1992-04-08 | — | — | CN | disclosed |
| EP-0471358-A1 | Fluoroethylcamptothecin derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |
| US-5061800-A | ANTITUMOR AGENTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0325247-A1 | Camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-07-26 | — | — | EP | disclosed |