Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | PTPRC | P08575 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043479 | 0.93 | HPGD (0.49) | KMT2AMEN1PTPRCPTPN1PTPN2 | |
| SCHEMBL9041961 | 0.93 | HPGD (0.49) | KMT2AMEN1PTPRCPTPN1PTPN2 | |
| SCHEMBL9041737 | 0.82 | HRH3 (0.52) | KMT2AMEN1PTPRCPTPN1PTPN2 | |
| SCHEMBL6691345 | 0.79 | KDM4E (0.43) | KMT2AMEN1CYSLTR2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6132820 | 0.79 | MEN1 (0.52) | KMT2AMEN1CYSLTR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9043802 | 0.78 | MAPT (0.48) | KMT2AMEN1KDM4EHPGD | |
| SCHEMBL9042966 | 0.78 | MAPT (0.48) | KMT2AMEN1KDM4EHPGD | |
| SCHEMBL9043630 | 0.78 | KMT2A (0.39) | KMT2AMEN1PTPRCPTPN1PTPN2 | |
| SCHEMBL6693620 | 0.77 | KDM4E (0.44) | KMT2AMEN1KDM4EL3MBTL1HPGD | |
| SCHEMBL9042971 | 0.77 | PTPRC (0.67) | KMT2AMEN1PTPRCPTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | claimed |
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |