⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19886830 | 0.67 | — | — | |
| SCHEMBL23189002 | 0.66 | — | — | |
| SCHEMBL13162792 | 0.65 | — | — | |
| SCHEMBL12186237 | 0.65 | — | — | |
| SCHEMBL13663709 | 0.62 | — | — | |
| SCHEMBL24448995 | 0.58 | — | — | |
| SCHEMBL7457130 | 0.56 | — | — | |
| SCHEMBL2227082 | 0.56 | — | — | |
| SCHEMBL24162597 | 0.54 | — | — | |
| SCHEMBL14455183 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107805262-B | A kind of production method of chlopyrifos | 江苏丰山集团股份有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-107805262-A | A kind of production method of chlopyrifos | 江苏丰山集团股份有限公司 | 2018-03-16 | — | — | CN | claimed |
| CN-117736182-A | MetTL3 inhibitors and uses thereof | 成都先导药物开发股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4306529-A2 | FGFR INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2020231990-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2020-11-19 | — | — | WO | disclosed |
| CN-107805262-B | A kind of production method of chlopyrifos | 江苏丰山集团股份有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-107805262-B | A kind of production method of chlopyrifos | 江苏丰山集团股份有限公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-110234646-A | Tau protein targeting PROTAC and related methods of use | 阿尔维纳斯股份有限公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-107805262-A | A kind of production method of chlopyrifos | 江苏丰山集团股份有限公司 | 2018-03-16 | — | — | CN | disclosed |
| CN-106414445-A | Compound and application thereof in expansion of hematopoietic stem cells and/or hematopoietic progenitor cells | 蒙特利尔大学 | 2017-02-15 | — | — | CN | disclosed |
| EP-2890696-A1 | QUINAZOLINONE COMPOUNDS AND DERIVATIVES THEREOF | AMGEN, INC. (US) | 2015-07-08 | — | — | EP | disclosed |
| EP-2217578-B9 | [1,2,4]TRIAZOLO[1,5-A]PYRIDINE AND [1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE COMPOUNDS AND THEIR USE | CANCER REC TECH LTD (GB) | 2014-09-10 | — | — | EP | disclosed |
| WO-2014036022-A1 | QUINAZOLINONE COMPOUNDS AND DERIVATIVES THEREOF | AMGEN INC. (US) | 2014-03-06 | — | — | WO | disclosed |
| CN-1309561-A | Therapeutic agent for erectile dysfunction | MOCHIDA PHARM CO LTD (JP) | 2001-08-22 | — | — | CN | disclosed |
| EP-0742717-A1 | BICYCLIC COMPOUNDS CAPABLE OF INHIBITING TYROSINE KINASES OF THE EPIDERMAL GROWTH FACTOR RECEPTOR FAMILY | WARNER-LAMBERT COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |