Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 4/20 | 0.75 |
| ▸ | TACR1 | P25103 | 4/20 | 0.75 |
| ▸ | TACR3 | P29371 | 1/20 | 0.75 |
| ▸ | HRH1 | P35367 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355803 | 0.94 | TACR2 (0.81) | TACR2TACR1TACR3HRH1 | |
| Hydrochloric Acid SCHEMBL8640236 | 0.93 | TACR2 (0.80) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL7829967 | 0.90 | TACR2 (0.88) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL7829976 | 0.90 | TACR2 (0.88) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL8640031 | 0.87 | TACR2 (0.75) | TACR2TACR1TACR3HRH1 | |
| Hydrochloric Acid SCHEMBL4354212 | 0.86 | TACR2 (0.97) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL4208407 | 0.86 | TACR2 (1.00) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL4208415 | 0.86 | TACR2 (1.00) | TACR2TACR1TACR3HRH1 | |
| SCHEMBL4208412 | 0.86 | TACR2 (1.00) | TACR2TACR1TACR3HRH1 | |
| Hydrochloric Acid SCHEMBL15798575 | 0.85 | TACR2 (0.98) | TACR2TACR1TACR3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696280-A1 | SUBSTITUTED PYRROLIDIN-3-YL-ALKYL-PIPERIDINES USEFUL AS TACHYKININ ANTAGONISTS | MERRELL DOW PHARMA (US) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994026735-A1 | SUBSTITUTED PYRROLIDIN-3-YL-ALKYL-PIPERIDINES USEFUL AS TACHYKININ ANTAGONISTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-11-24 | — | — | WO | disclosed |