⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10829285 | 0.80 | — | — | |
| SCHEMBL13149193 | 0.76 | HRH3 (0.34) | — | |
| SCHEMBL14155185 | 0.75 | — | — | |
| SCHEMBL8348136 | 0.75 | — | — | |
| SCHEMBL10142464 | 0.75 | — | — | |
| SCHEMBL14147593 | 0.75 | — | — | |
| SCHEMBL1400990 | 0.75 | — | — | |
| SCHEMBL6012887 | 0.75 | — | — | |
| SCHEMBL525984 | 0.75 | — | — | |
| SCHEMBL1149444 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743944-A1 | AZACYCLIC DERIVATIVES | SmithKline Beecham Farmaceutici S.p.A. (IT) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021843-A1 | AZACYCLIC DERIVATIVES | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1995-08-17 | — | — | WO | disclosed |
| US-5322848-A | Analgesics | DR. LO ZEMBELETTI S.P.A. (IT) | 1994-06-21 | — | — | US | disclosed |
| EP-0501997-A1 | N-ACYL-SUBSTITUTED AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICALS. | ZAMBELETTI SPA L (IT) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991017981-A1 | AZACYCLIC DERIVATIVES | DR. LO. ZAMBELETTI S.P.A. (IT) | 1991-11-28 | — | — | WO | disclosed |
| WO-1991008206-A1 | N-ACYL-SUBSTITUTED AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICALS | DR. LO. ZAMBELETTI S.P.A. (IT) | 1991-06-13 | — | — | WO | disclosed |