Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 9/20 | 0.62 |
| ▸ | EDNRB | P24530 | 5/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046624 | 0.89 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL9047630 | 0.86 | EDNRA (0.47) | EDNRAEDNRBPIK3CG | |
| SCHEMBL9045564 | 0.86 | EDNRA (0.43) | EDNRAEDNRBESR1 | |
| SCHEMBL9047114 | 0.84 | EDNRA (0.82) | EDNRAEDNRBPIK3CG | |
| SCHEMBL9493332 | 0.83 | EDNRA (0.77) | EDNRAEDNRB | |
| SCHEMBL9045073 | 0.81 | EDNRA (0.62) | EDNRAEDNRBESR1 | |
| SCHEMBL9045387 | 0.80 | EDNRA (0.65) | EDNRAEDNRB | |
| SCHEMBL9046504 | 0.80 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL9044684 | 0.79 | EDNRA (0.59) | EDNRAEDNRB | |
| SCHEMBL9045375 | 0.78 | EDNRA (0.74) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510526-B1 | Use of sulfonamides as drug and new sulfonamides | HOFFMANN LA ROCHE (CH) | 1996-12-04 | — | — | EP | claimed |
| EP-0510526-A1 | Use of sulfonamides as drug and new sulfonamides | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1992-10-28 | — | — | EP | claimed |