Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 10/20 | 0.44 |
| ▸ | DPP4 | P27487 | 4/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049641 | 1.00 | PREP (0.44) | PREPDPP4FAPDPP8FAAH | |
| SCHEMBL9051819 | 0.95 | PREP (0.43) | PREPDPP4FAPDPP8 | |
| SCHEMBL9048078 | 0.84 | PREP (0.52) | PREPDPP4FAPDPP8 | |
| SCHEMBL9048922 | 0.84 | PREP (0.52) | PREPDPP4FAPDPP8 | |
| SCHEMBL9050174 | 0.84 | PREP (0.54) | PREP | |
| SCHEMBL9049570 | 0.83 | PREP (0.52) | PREPDPP4 | |
| SCHEMBL9051117 | 0.83 | PREP (0.49) | PREPDPP4 | |
| SCHEMBL9050430 | 0.83 | PREP (0.49) | PREPDPP4 | |
| SCHEMBL9049633 | 0.82 | PREP (0.42) | PREPDPP4FAPDPP8FAAH | |
| SCHEMBL9045355 | 0.82 | PREP (0.42) | PREPDPP4FAPDPP8FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |