Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 7/20 | 0.59 |
| ▸ | EDNRB | P24530 | 4/20 | 0.59 |
| ▸ | AR | P10275 | 6/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044594 | 0.88 | EDNRA (0.78) | EDNRAEDNRBARBCL2L1MCL1 | |
| SCHEMBL9045571 | 0.88 | EDNRA (0.78) | EDNRAEDNRBARBCL2L1MCL1 | |
| SCHEMBL9677279 | 0.86 | AR (0.55) | ARBCL2L1FFAR1MCL1POLB | |
| SCHEMBL9044052 | 0.77 | EDNRA (0.89) | EDNRAEDNRB | |
| SCHEMBL9045921 | 0.76 | AR (0.64) | EDNRAEDNRBARBCL2L1MCL1 | |
| SCHEMBL9044679 | 0.76 | AR (0.64) | EDNRAEDNRBARBCL2L1MCL1 | |
| SCHEMBL8655641 | 0.74 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL9044397 | 0.74 | EDNRA (0.82) | EDNRAEDNRB | |
| SCHEMBL9046379 | 0.74 | EDNRA (0.91) | EDNRAEDNRB | |
| SCHEMBL9044364 | 0.74 | EDNRA (0.79) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510526-B1 | Use of sulfonamides as drug and new sulfonamides | HOFFMANN LA ROCHE (CH) | 1996-12-04 | — | — | EP | claimed |