Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 13/20 | 0.68 |
| ▸ | EDNRB | P24530 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DHPS | P49366 | 2/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045387 | 0.90 | EDNRA (0.65) | EDNRAEDNRBDHPSABCC3ABCC4 | |
| SCHEMBL9047114 | 0.83 | EDNRA (0.82) | EDNRAEDNRBDHPSABCC3ABCC4 | |
| SCHEMBL9053901 | 0.83 | EDNRA (0.80) | EDNRAEDNRBDHPSABCC3ABCC4 | |
| SCHEMBL9044668 | 0.81 | EDNRA (0.78) | EDNRAEDNRBDHPSABCC3ABCC4 | |
| SCHEMBL9045783 | 0.81 | EDNRA (0.78) | EDNRAEDNRBDHPSABCC3ABCC4 | |
| SCHEMBL9046873 | 0.81 | EDNRA (1.00) | EDNRAEDNRBDHPSABCC3ABCC4 | |
| SCHEMBL9046624 | 0.81 | EDNRA (0.78) | EDNRAEDNRBDHPSABCC3ABCC4 | |
| SCHEMBL9493332 | 0.80 | EDNRA (0.77) | EDNRAEDNRBDHPSABCC3ABCC4 | |
| SCHEMBL9044370 | 0.80 | EDNRA (0.77) | EDNRAEDNRBDHPSABCC3ABCC4 | |
| SCHEMBL9045999 | 0.80 | EDNRA (0.85) | EDNRAEDNRBDHPSABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510526-B1 | Use of sulfonamides as drug and new sulfonamides | HOFFMANN LA ROCHE (CH) | 1996-12-04 | — | — | EP | claimed |