Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 9/20 | 0.70 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045793 | 1.00 | PREP (0.70) | PREPADAM10MMP1MMP2MMP3 | |
| SCHEMBL9047773 | 0.91 | PREP (0.60) | PREPADAM10MMP1MMP2MMP3 | |
| SCHEMBL9047776 | 0.91 | PREP (0.60) | PREPADAM10MMP1MMP2MMP3 | |
| SCHEMBL9048765 | 0.90 | PREP (0.76) | PREPADAM10MMP1MMP2MMP3 | |
| SCHEMBL9050265 | 0.90 | PREP (0.65) | PREPADAM10MMP1MMP2MMP3 | |
| SCHEMBL9050274 | 0.90 | PREP (0.65) | PREPADAM10MMP1MMP2MMP3 | |
| SCHEMBL9049856 | 0.83 | POLB (0.48) | PREP | |
| SCHEMBL9049850 | 0.83 | POLB (0.48) | PREP | |
| SCHEMBL9047530 | 0.82 | PREP (0.76) | PREPADAM10MMP1MMP2MMP3 | |
| SCHEMBL9046528 | 0.81 | PREP (0.55) | PREPADAM10MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |