Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091078 | 0.89 | DPP4 (0.56) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9045946 | 0.87 | DPP4 (0.43) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL8083110 | 0.87 | DPP4 (0.52) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9046856 | 0.85 | DPP4 (0.46) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9045700 | 0.83 | DPP4 (0.41) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10655952 | 0.82 | DPP4 (0.50) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL8083142 | 0.81 | DPP4 (0.49) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL11000701 | 0.79 | DPP4 (0.48) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10654892 | 0.79 | DPP4 (0.58) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10653563 | 0.78 | KMT2A (0.54) | DPP4CHRM2DRD1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |