Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 9/20 | 0.37 |
| ▸ | HTR7 | P34969 | 9/20 | 0.37 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047474 | 0.97 | PREP (0.48) | PREPHTR1AHTR7ADAM10MMP1 | |
| SCHEMBL9049239 | 0.95 | PREP (0.52) | PREPHTR1AHTR7ADAM10MMP1 | |
| SCHEMBL9050451 | 0.90 | PREP (0.61) | PREPHTR1AHTR7ADAM10MMP1 | |
| SCHEMBL9049484 | 0.86 | PREP (0.48) | PREPHTR1AHTR7ADAM10MMP1 | |
| SCHEMBL9046320 | 0.83 | PREP (0.47) | PREPHTR1AHTR7ADAM10MMP1 | |
| SCHEMBL9048816 | 0.81 | POLB (0.46) | PREPHRH3KDM4E | |
| SCHEMBL9047283 | 0.81 | PREP (0.59) | PREPADAM10MMP1MMP2MMP3 | |
| SCHEMBL9049063 | 0.80 | PREP (0.52) | PREPHTR1AHTR7ADAM10MMP1 | |
| SCHEMBL9046264 | 0.76 | PREP (0.59) | PREPADAM10MMP1MMP2MMP3 | |
| SCHEMBL9050374 | 0.76 | PREP (0.64) | PREPADAM10MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |