Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170801 | 0.92 | MAPK1 (0.48) | MAPK1DRD3 | |
| SCHEMBL13916556 | 0.92 | MAPK1 (0.48) | MAPK1DRD3 | |
| SCHEMBL13743617 | 0.82 | DRD3 (0.30) | DRD3 | |
| SCHEMBL3913743 | 0.82 | DRD3 (0.30) | DRD3 | |
| SCHEMBL15177748 | 0.71 | DRD3 (0.33) | DRD3 | |
| SCHEMBL17278812 | 0.70 | — | — | |
| SCHEMBL5234235 | 0.67 | MAPK1 (0.46) | MAPK1LMNACYP2C9CHRM2CHRM1 | |
| SCHEMBL14434408 | 0.67 | MAPK1 (0.46) | MAPK1LMNACYP2C9CHRM2CHRM1 | |
| SCHEMBL31719552 | 0.67 | DRD3 (0.40) | DRD3 | |
| SCHEMBL16588995 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749966-A1 | 5-HT 3 RECEPTOR AGONIST, NOVEL THIAZOLE DERIVATIVE, AND INTERMEDIATE THEREFOR | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |