SCHEMBL9048174

SCHEMBL9048174

FC(F)(F)c1cccc(-c2cnc(-c3ccc(Cl)cc3)[nH]2)c1

nearest known ligand 0.80

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 7/20 0.80
NPY5R Q15761 4/20 0.68
CNR2 P34972 6/20 0.56
CNR1 P21554 3/20 0.54
TRPV1 Q8NER1 1/20 0.53
HRH1 P35367 1/20 0.53
HRH4 Q9H3N8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28540057 0.89 SCN2A (1.00) SCN2ANPY5RCNR2CNR1TRPV1
SCHEMBL19443413 0.83 SCN2A (0.74) SCN2ANPY5RCNR2CNR1TRPV1
SCHEMBL19443358 0.78 SCN2A (0.73) SCN2ANPY5RCNR2CNR1TRPV1
SCHEMBL20428529 0.78 SCN2A (0.68) SCN2ANPY5RCNR2CNR1HRH1
SCHEMBL22668206 0.77 SCN2A (0.86) SCN2ANPY5RTRPV1
SCHEMBL6699426 0.76 SCN2A (0.71) SCN2ANPY5RCNR2CNR1HRH1
SCHEMBL24427804 0.76 SCN2A (0.70) SCN2ANPY5RCNR2CNR1HRH1
SCHEMBL15707579 0.74 SCN2A (0.56) SCN2ANPY5RCNR2
SCHEMBL15707442 0.74 SCN2A (0.56) SCN2ANPY5RCNR2CNR1
SCHEMBL15707315 0.74 SCN2A (0.56) SCN2ANPY5RCNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0712847-A1 IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL DRUG NIPPON SODA CO., LTD. (JP) 1996-05-22 EP disclosed