Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049500 | 0.97 | PREP (0.41) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9047689 | 0.95 | PREP (0.42) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9050644 | 0.91 | PREP (0.47) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9047864 | 0.88 | PREP (0.41) | PREPHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL9049083 | 0.86 | PREP (0.41) | PREPHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL9048506 | 0.83 | CHRM2 (0.39) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9049973 | 0.83 | PREP (0.42) | PREPHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL9048872 | 0.82 | PREP (0.38) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9049657 | 0.82 | PREP (0.39) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9049419 | 0.82 | PREP (0.39) | PREPCHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |