Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | B3GNT2 | Q9NY97 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30838374 | 0.85 | POLB (1.00) | POLBALDH1A1HPGDDAOMEN1 | |
| SCHEMBL828232 | 0.85 | POLB (1.00) | POLBALDH1A1HPGDDAOMEN1 | |
| SCHEMBL10833903 | 0.83 | POLB (0.70) | POLBALDH1A1HPGDDAOMEN1 | |
| SCHEMBL10736441 | 0.82 | POLB (0.74) | POLBALDH1A1HPGDDAOMEN1 | |
| SCHEMBL7017890 | 0.82 | POLB (0.74) | POLBALDH1A1HPGDDAOMEN1 | |
| SCHEMBL7443237 | 0.79 | POLB (0.70) | POLBALDH1A1HPGDDAOMEN1 | |
| SCHEMBL14828721 | 0.79 | POLB (0.70) | POLBALDH1A1HPGDDAOMEN1 | |
| SCHEMBL7513143 | 0.78 | POLB (0.68) | POLBALDH1A1HPGDDAOMEN1 | |
| SCHEMBL23997201 | 0.78 | POLB (0.68) | POLBALDH1A1HPGDDAOMEN1 | |
| SCHEMBL30336952 | 0.78 | POLB (0.68) | POLBALDH1A1HPGDDAOMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143444-A2 | DIPHENYLBUTYPIPERIDINE AUTOPHAGY INDUCERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-11-17 | — | — | WO | disclosed |