Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 4/20 | 0.31 |
| ▸ | FAP | Q12884 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049093 | 0.92 | PREP (0.38) | PREPACHEDPP4FAP | |
| SCHEMBL9045657 | 0.86 | DPP4 (0.44) | PREPDPP4FAP | |
| SCHEMBL9048450 | 0.85 | PREP (0.34) | PREPHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL9047458 | 0.84 | PREP (0.37) | PREPDPP4FAP | |
| SCHEMBL9049071 | 0.83 | PREP (0.33) | PREPHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL9049184 | 0.82 | PREP (0.47) | PREPDPP4 | |
| SCHEMBL9050430 | 0.82 | PREP (0.49) | PREPDPP4 | |
| SCHEMBL9051117 | 0.82 | PREP (0.49) | PREPDPP4 | |
| SCHEMBL9048070 | 0.81 | PREP (0.46) | PREPDPP4 | |
| SCHEMBL9049570 | 0.80 | PREP (0.52) | PREPDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |