Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049856 | 0.89 | POLB (0.48) | PREPPOLBMAPTALDH1A1HPGD | |
| SCHEMBL9049850 | 0.89 | POLB (0.48) | PREPPOLBMAPTALDH1A1HPGD | |
| SCHEMBL9048099 | 0.85 | PREP (0.52) | PREPPOLBMAPTALDH1A1HPGD | |
| SCHEMBL9048765 | 0.83 | PREP (0.76) | PREP | |
| SCHEMBL5092539 | 0.83 | MAPT (0.59) | PREPPOLBMAPTALDH1A1HPGD | |
| SCHEMBL9045852 | 0.83 | PREP (0.53) | PREPPOLBMAPTALDH1A1HPGD | |
| SCHEMBL9045858 | 0.83 | PREP (0.53) | PREPPOLBMAPTALDH1A1HPGD | |
| SCHEMBL9050374 | 0.81 | PREP (0.64) | PREP | |
| SCHEMBL9051072 | 0.80 | POLB (0.44) | PREPPOLBMAPTALDH1A1HPGD | |
| SCHEMBL9051077 | 0.80 | POLB (0.44) | PREPPOLBMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |