Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27745842 | 1.00 | CYP3A4 (0.40) | CYP3A4CYP2C9SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9048563 | 1.00 | CYP3A4 (0.40) | CYP3A4CYP2C9SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9048580 | 1.00 | CYP3A4 (0.40) | CYP3A4CYP2C9SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL27745843 | 1.00 | CYP3A4 (0.40) | CYP3A4CYP2C9SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL4456248 | 0.92 | CYP3A4 (0.44) | CYP3A4CYP2C9SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8170512 | 0.92 | CYP3A4 (0.44) | CYP3A4CYP2C9SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL4454947 | 0.92 | CYP3A4 (0.44) | CYP3A4CYP2C9SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL2861462 | 0.92 | CYP3A4 (0.44) | CYP3A4CYP2C9SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL4456242 | 0.92 | CYP3A4 (0.44) | CYP3A4CYP2C9SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL4454944 | 0.92 | CYP3A4 (0.44) | CYP3A4CYP2C9SMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |