Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 12/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442223 | 0.97 | PREP (0.48) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7302389 | 0.95 | PREP (0.47) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9049670 | 0.94 | PREP (0.47) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9049709 | 0.93 | PREP (0.46) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7295277 | 0.92 | PREP (0.59) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7434400 | 0.90 | PREP (0.58) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9048703 | 0.85 | PREP (0.41) | PREP | |
| SCHEMBL9049491 | 0.83 | PREP (0.45) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9049675 | 0.82 | PREP (0.48) | PREPCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9048594 | 0.82 | PREP (0.48) | PREPCHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |