Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.30 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810617 | 1.00 | TSHR (0.41) | TSHRFAAHTRPV1PRKCAHIF1A | |
| SCHEMBL8813950 | 1.00 | TSHR (0.41) | TSHRFAAHTRPV1PRKCAHIF1A | |
| SCHEMBL8811516 | 1.00 | TSHR (0.41) | TSHRFAAHTRPV1PRKCAHIF1A | |
| SCHEMBL8810579 | 1.00 | TSHR (0.41) | TSHRFAAHTRPV1PRKCAHIF1A | |
| SCHEMBL8812307 | 1.00 | TSHR (0.41) | TSHRFAAHTRPV1PRKCAHIF1A | |
| SCHEMBL9422996 | 1.00 | TSHR (0.41) | TSHRFAAHTRPV1PRKCAHIF1A | |
| SCHEMBL12250902 | 0.92 | TSHR (0.44) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL30185811 | 0.92 | TSHR (0.44) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL8813126 | 0.88 | TSHR (0.44) | TSHRFAAHTRPV1PRKCAHIF1A | |
| SCHEMBL8814288 | 0.88 | TSHR (0.44) | TSHRFAAHTRPV1PRKCAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |