Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 16/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048775 | 1.00 | PREP (0.55) | PREPF2CHRM2CHRM4CHRM1 | |
| SCHEMBL9047270 | 0.95 | PREP (0.53) | PREPF2 | |
| SCHEMBL9047276 | 0.95 | PREP (0.53) | PREPF2 | |
| SCHEMBL9046605 | 0.90 | PREP (0.69) | PREP | |
| SCHEMBL9046610 | 0.90 | PREP (0.69) | PREP | |
| SCHEMBL9047461 | 0.90 | PREP (0.54) | PREP | |
| SCHEMBL9047466 | 0.90 | PREP (0.54) | PREP | |
| SCHEMBL9050257 | 0.89 | PREP (0.51) | PREP | |
| SCHEMBL9050255 | 0.89 | PREP (0.51) | PREP | |
| SCHEMBL9046994 | 0.87 | PREP (0.67) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536399-B1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5407950-A | Brain disorders, senile dementia | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0536399-A1 | NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-14 | — | — | EP | disclosed |