Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | HTR5A | P47898 | 3/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620819 | 0.79 | DYRK1A (0.35) | DYRK1A | |
| Hydrochloric Acid SCHEMBL8523808 | 0.78 | DYRK1A (0.34) | DYRK1A | |
| SCHEMBL3851653 | 0.78 | KDM4E (0.34) | DRD4 | |
| Benzodiazepine SCHEMBL7160172 | 0.72 | GAA (0.44) | — | |
| Benzodiazepine SCHEMBL8137 | 0.72 | GAA (0.44) | — | |
| Benzodiazepine SCHEMBL3414245 | 0.72 | GAA (0.40) | — | |
| Benzodiazepine SCHEMBL4700331 | 0.71 | GAA (0.43) | — | |
| Benzodiazepine SCHEMBL6618830 | 0.71 | GAA (0.43) | — | |
| Benzodiazepine SCHEMBL936208 | 0.71 | GAA (0.43) | — | |
| Benzodiazepine SCHEMBL11484022 | 0.71 | GAA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264797-B1 | Benzodiazepines assay, tracers, immunogens and antibodies | ABBOTT LAB (US) | 1996-01-10 | — | — | EP | disclosed |
| EP-0264797-A2 | Benzodiazepines assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1988-04-27 | — | — | EP | disclosed |
| US-4060608-A | TRANQUILIZERS, SEDATIVE, HYPNOSIS INDUCER | DDSA PHARMACEUTICALS (EN) | 1977-11-29 | — | — | US | disclosed |